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Towards Accurate and Automated TMS Coil Placement with A Robotic System in MRI: A Preliminary Study
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Alfredo De Goyeneche and Naichen Zhao and Charles Paxson and Binghan He and Ron Fearing and Stella X. Yu and Chunlei Liu and Michael Lustig
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Annual Meeting International Society for Magnetic Resonance in Medicine, Honolulu, Hawaii, 10-15 May 2025
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Paper
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Abstract
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Precise TMS control within MRI is fundamental for clinical and neuroscience advancements. However, challenges remain in accurate targeting, variability in functional anatomy, and real-time brain dynamics. We aim to develop a robotic system for accurate, automated TMS coil placement inside MRI. We developed a 3DOF robotic system to place a mock TMS coil within the MRI environment. Wireless markers identify the end effector’s position through fast projection acquisitions, enabling closed-loop adjustments for accurate positioning. We showcase our robotic and localization system working within the MRI environment, detailing the placement precision achieved during initial trials. This system demonstrates capacity for precise, automated TMS coil positioning within the MRI, laying a foundation for fully integrated TMS-MRI setups. This approach will facilitate patient-specific, adaptive stimulation, enabling studies on dynamic brain-state-driven stimulation and improving clinical reproducibility.
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Keywords
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hybrid and novel systems technology, multimodal
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